Looking for recommendations on where to go in Panama

Hey guys I'm visiting Panama for the first time for a delayed 40th birthday celebration. Going for a week of fishing and looking to sample the local talent. Looks like that is the easy part. My question is whats the best hotel to stay in Panama city. Looking to stay in a nice and secure hotel near the action while waiting to be transported to our fishing destination. I speak no Spanish so I'm thinking language barrier may be a issue for me as well. Thanks in advance