Hi Destiny!
Don't worry about what others say, there's so much in Houston that girls with differing menus still can be successful. No matter what you do, just be damn good at it!
I recommend staying near the galleria. It is more west of downtown, but still very accesible. I've also noticed some touring gals targeting specific areas of the city. Houston is the 4th largest city in the US; only behind NYC, LA and Chicago. With that said, if you set up shop in the Galleria, guys who live/work way north or south may not be able to see you. It might not be a bad idea to work south Houston (Clear Lake, Baybrook, Galveston, etc) or north Houston (Woodlands, Conroe, Spring, etc). There are lots of great guys there who don't get to visit with many ladies simply because of the distance. You might wanna try that.
Whatever you do, be safe and screen. The Houston providers are very nice and helpful and nearly all give prompt reference requests. Good luck!