Steroid dexamethasone reduces deaths among patients with severe COVID-19 - trial shows

  • oeb11
  • 06-16-2020, 10:08 AM
https://www.msn.com/en-us/health/hea...OUf?li=BBnb7Kz


LONDON, June 16 (Reuters) - A cheap and widely-used steroid called dexamethasone has become the first drug shown to be able to save lives among COVID-19 patients in what s
Trial results announced on Tuesday showed dexamethasone, which is used to reduce inflammation in other diseases such as arthritis, reduced death rates by around a third among the most severely ill of COVID-19 patients admitted to hospital.

The results suggest the drug should immediately become standard care in patients with severe cases of the pandemic disease, said the researchers who led the trials. Britain's health minister said the state-run health service's standard hospital treatment for COVID-19 would include the drug from Tuesday afternoon, adding that Britain had stockpiled 200,000 courses of the treatment.
"This is a (trial) result that shows that if patients who have COVID-19 and are on ventilators or are on oxygen are given dexamethasone, it will save lives, and it will do so at a remarkably low cost," said Martin Landray, an Oxford University professor co-leading the trial, known as the RECOVERY trial.
"It's going to be very hard for any drug really to replace this, given that for less than 50 pounds ($63.26), you can treat eight patients and save a life," he said in an online briefing.
His co-lead investigator, Peter Horby, said dexamethasone was "the only drug that's so far shown to reduce mortality - and it reduces it significantly."
"It is a major breakthrough," he said. "Dexamethasone is inexpensive, on the shelf, and can be used immediately to save lives worldwide."
There are currently no approved treatments or vaccines for COVID-19, the disease caused by the new coronavirus which has killed more than 431,000 people globally.
SAVE LIVES AROUND THE WORLD
England's chief medical officer, Chris Whitty, said Tuesday's announcement was "the most important trial result for COVID-19 so far," adding: "It will save lives around the world."
The RECOVERY trial compared outcomes of around 2,100 patients who were randomly assigned to get the steroid, with those of around 4,300 patients who did not get it. The results suggest that one death would be prevented by treatment with dexamethasone among every eight ventilated COVID-19 patients,
Landray said, and one death would be prevented among every 25 COVID-19 patients that received the drug and are on oxygen.
Among patients with COVID-19 who did not require respiratory support, there was no benefit from treatment with dexamethasone.
"The survival benefit is clear and large in those patients who are sick enough to require oxygen treatment, so dexamethasone should now become standard of care in these patients," Horby said.
The RECOVERY trial was launched in April as a randomized clinical trial to test a range of potential treatments for COVID-19, including low-dose dexamethasone and the malaria drug hydroxychloroquine. The hydroxychloroquine arm was halted earlier this month after Horby and Landray said results showed it was "useless" at treating COVID-19 patients.


Interesting trial of a commonly available steroid drug used to treat inflammation and other problems. FDA approved in the US and can be used off label for Wuhan virus.

The use and complications of steroid tratment are well known, and physicians are well versed in these drugs.

Sounds like a reasonable use for Dexamethason in severe and moderate cases of patients hospitalized with wuhan virus. Likely not recommended in asymptomatic or minimally symptomatic non-hosptialized patients. No need.



Now - all that needs to be done is to have President Trump advocate for use of the drug - and all the Lib DPST will recoil in horror and refuse. Particularly among the terrorists in Seattle.

which would increase the case mortality rate among certain LibDPST populations.



I am not one to advocate for increased mortality rates among any human beings.

People will make their own choices.
A bit of a shame j66 is out - his medical expertise from a fireman's viewpoint would have been entertaining.


Still - we have 9500 to post memes of robespierre, YSL, Lenny bruce and other irrelevant dead historical figures.
9500 has me on "Ignore" - so would One of You wonderful humanitarian Libs please get the message about dexamethasone to 9500- in case he/she might need to know. Thank You in advance.
adav8s28's Avatar
https://www.msn.com/en-us/health/hea...OUf?li=BBnb7Kz

Now - all that needs to be done is to have President Trump advocate for use of the drug -
Originally Posted by oeb11
The dexamethasone looks like it could help patients. The last time Trump was an advocate for something, he wanted doctors to have nurses put a couple of drops of pine sol or Mr. Clean to the patients IV to clear the virus.



Unique_Carpenter's Avatar
There's over a dozen steroids out there, that have been shown to be useful. The real issue is which one is correct for a specific patient.
The one mentioned I'm familiar with as we've used horse size doses in older horses with arthritis.
But yes, it helps clear lungs a bit also.
The dexamethasone looks like it could help patients. The last time Trump was an advocate for something, he wanted doctors to have nurses put a couple of drops of pine sol or Mr. Clean to the patients IV to clear the virus.



Originally Posted by adav8s28
And this is why your posts have absolutely no credibility.

This is not what Trump said.

But carry on with your DemPanic lies.

  • oeb11
  • 06-16-2020, 03:11 PM
Agree with EL - the credibility of the poster suffers when flagrant Lies are posted.
i predicted the LibDPST response When i mentioned Trump - and just like clockwork - the predicted response.
adav8s28's Avatar

This is not what Trump said.
Originally Posted by eccielover
Trump said to inject a CV19 patient with a disinfectant. What do you think Pine Sol is Numbnuts?

His staff and the CV19 response team were shocked by his comments.

From the link:

As Trump went off script to suggest people with the virus could be cured by UV rays or disinfectants “by injection inside,” White House officials began texting one another to ask where he got that idea because they thought, as one adviser put it, “this was going to be bad.”


https://www.nbcnews.com/politics/whi...ocked-n1192031
dilbert firestorm's Avatar
Trump said to inject a CV19 patient with a disinfectant. What do you think Pine Sol is Numbnuts?

His staff and the CV19 response team were shocked by his comments.

From the link:

As Trump went off script to suggest people with the virus could be cured by UV rays or disinfectants “by injection inside,” White House officials began texting one another to ask where he got that idea because they thought, as one adviser put it, “this was going to be bad.”


https://www.nbcnews.com/politics/whi...ocked-n1192031 Originally Posted by adav8s28

trump was not talking about pine sols. there are medical grade disinfectants which have been in use since the 1990's. they are used to clean the blood supply of bugs. thats the stuff trump was referring to, most average people including reporters won't know about this medical stuff.
  • oeb11
  • 06-17-2020, 07:42 AM
Trump said to inject a CV19 patient with a disinfectant. What do you think Pine Sol is Numbnuts?

His staff and the CV19 response team were shocked by his comments.

From the link:

As Trump went off script to suggest people with the virus could be cured by UV rays or disinfectants “by injection inside,” White House officials began texting one another to ask where he got that idea because they thought, as one adviser put it, “this was going to be bad.”


https://www.nbcnews.com/politics/whi...ocked-n1192031 Originally Posted by adav8s28

If it were not for Lies - the Libs would have absolutely nothing to contribute. Shameless in their hatred of Trump - and willingness to go to any lengths, means, or acts to discredit the POTUS.

class Act - Not - "a".


OP contributed an article about progress in treating the wuhan virus - and like clockwork - the hate Trump and everything is trump's fault brigade arrives to hi-jack the message.

U are welcome to formulate a controlled study of volunteers to test Trump's "recommendation". should be quite a number of volunteers in the Lib group - if U offer a free "Che" t-shirt for participation!
If it were not for Lies - the Libs would have absolutely nothing to contribute. Shameless in their hatred of Trump - and willingness to go to any lengths, means, or acts to discredit the POTUS.

class Act - Not - "a".


OP contributed an article about progress in treating the wuhan virus - and like clockwork - the hate Trump and everything is trump's fault brigade arrives to hi-jack the message.

U are welcome to formulate a controlled study of volunteers to test Trump's "recommendation". should be quite a number of volunteers in the Lib group - if U offer a free "Che" t-shirt for participation! Originally Posted by oeb11
Yeah, even their beloved Politifact couldn't dispute that Trump was being taken out of context.

https://www.politifact.com/article/2...disinfectant-/

The briefing transcript shows that Trump did not say people should inject themselves with bleach or alcohol to treat the coronavirus. He was asking officials on the White House coronavirus task force whether they could be used in potential cures.
But it's not surprising coming from a poster who stuck by a 6 million deaths in the US projection as well as still believes a fever of 100.4 or above would indicate Wuhan virus over the flu.

Lying, misrepresentation, and DemPanic are all part of his/her calling card.
  • oeb11
  • 06-17-2020, 02:36 PM
EL - accurately written.

Thanku , good Sir!
adav8s28's Avatar
Yeah, even their beloved Politifact couldn't dispute that Trump was being taken out of context.

https://www.politifact.com/article/2...disinfectant-/
Originally Posted by eccielover
Nice try at damage control little "e". You left this paragraph out from your link. I wonder why.

The president first posed the question April 23 after William Bryan, undersecretary for science and technology at the Department of Homeland Security, presented a study that found sun exposure and cleaning agents like bleach have an adverse effect on the coronavirus. Bryan was referring to the use of disinfectants on surfaces and in aerosols, but Trump asked whether the chemicals could be used in a potential COVID-19 treatment, as well.

Notice the last sentence, Trump asked if the disinfectants (chemicals) could be used in a potential COVID-19 treatment.

How does a patient in a hospital get their medications? From an IV numbnuts. When the self proclaimed unstable genius asked if the disinfectants could be used in a treatment, well that would mean mixing in the disinfectants with the IV.

I didn't say or imply about anyone taking bleach at home. You are full of it little 'e'.
The_Waco_Kid's Avatar
Nice try at damage control little "e". You left this paragraph out from your link. I wonder why.

The president first posed the question April 23 after William Bryan, undersecretary for science and technology at the Department of Homeland Security, presented a study that found sun exposure and cleaning agents like bleach have an adverse effect on the coronavirus. Bryan was referring to the use of disinfectants on surfaces and in aerosols, but Trump asked whether the chemicals could be used in a potential COVID-19 treatment, as well.

Notice the last sentence, Trump asked if the disinfectants (chemicals) could be used in a potential COVID-19 treatment.

How does a patient in a hospital get their medications? From an IV numbnuts. When the self proclaimed unstable genius asked if the disinfectants could be used in a treatment, well that would mean mixing in the disinfectants with the IV.

I didn't say or imply about anyone taking bleach at home. You are full of it little 'e'. Originally Posted by adav8s28





even SorosFacts can't make your point for you.



what about Fauci the incompetent fraud? Trump didn't listen to him. Trump was right. Fauci is an idiot.



Fauci is a anti-Trump operative who intentionally tried to falsely advise Trump. Fauci should be executed for his crimes of mass murder.



Fauci is a self-righteous ass covering prig as they say in the UK
adav8s28's Avatar
even SorosFacts can't make your point for you.
Originally Posted by The_Waco_Kid
This politico link makes my point quite clearly. Trump asked if disinfectants could be used to treat CV19 patients. There is no getting around that. None.

https://www.politifact.com/article/2...disinfectant-/
The_Waco_Kid's Avatar
This politico link makes my point quite clearly. Trump asked if disinfectants could be used to treat CV19 patients. There is no getting around that. None.

https://www.politifact.com/article/2...disinfectant-/ Originally Posted by adav8s28



yes i can. politifact is left biased and you know that yet you believe everything George Soros tells them to say. politifact is about as reliable as as a weather forecast for next year.




https://www.allsides.com/news-source/politifact


so where is your 3 million dead from the scamdemic?
adav8s28's Avatar

so where is your 3 million dead from the scamdemic? Originally Posted by The_Waco_Kid
The first 90,000 deaths only one percent of the USA population were infected (about 3 million people). If 70% of the USA population becomes infected (about 200 million people) then the deaths will be in the 3 million range. Using Iovannidis equation.

Death Rate = # deaths/# infected

.015 = #deaths/ 200,000,000

#deaths = .015 * 200,000,000

#deaths = 3,000,000 people

Now that most states have opened things up, more people will get infected. Everyone is a potential host to the virus unless they have had it before and develop the antibodies.