Visiting San Jose this weekend

Will be visiting CR for the first time this upcoming weekend and will be staying downtown San Jose for a couple weeks. Any recommendations for someone that will be visiting without a car rental?

I'm looking for both the sure thing with outcalls to my hotel in downtown SJ but also spots where I can practice my hunting skills and hit up the Ticas and possibly score me some after some drinks.

Are there particular areas I for sure stay away? I imagine downtown SJ is pretty safe for the most part.