If the seafood is good the place will be crowded on Friday night. I like Wildfish and if you go before 5 you can probably sit at the bar for great happy hour selections - as long as you have a spot to sit wait won't be that long.
"Good" and "not slammed on Friday night" don't go together. Try Cappy's on Broadway.
Also the Culinary Institute of America Savor at the Pearl Brewery is good.