Airport area usually well accepted and Medical Center area, too.
Not sure when you are planning to be in SA but since there is a massive (60,000! or more) week long convention of SODAs (7th Day Adventists) commencing here right now likely hotel pricing is gonna be way higher than than normal and rooms tough to find.
No doubt some of the extended stay places might be available, and good luck in any case.
Hit up the usual travel websites, like Travelocity.com, Expedia.com, and others to get a gauge on availability and pricing before you hit the road.