The 1918 Spanish flu was a much more lethal strain of Influenza Virus - which killed rapidly by pulmonary transudation and edema. The Case Fatality rate was much higher.
The 1918 influenza pandemic was the most severe pandemic in recent history. It was caused by an H1N1 virus with genes of avian origin. Although there is not universal consensus regarding where the virus originated, it spread worldwide during 1918-1919. In the United States, it was first identified in military personnel in spring 1918. It is estimated that about 500 million people or one-third of the world’s population became infected with this virus. The number of deaths was estimated to be at least 50 million worldwide with about 675,000 occurring in the United States. 1918 Pandemic Video
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History of 1918 Flu Pandemic
Mortality was high in people younger than 5 years old, 20-40 years old, and 65 years and older. The high mortality in healthy people, including those in the 20-40 year age group, was a unique feature of this pandemic. While the
1918 H1N1 virus has been synthesized and evaluated, the properties that made it so devastating are not well understood. With no vaccine to protect against influenza infection and no antibiotics to treat secondary bacterial infections that can be associated with influenza infections, control efforts worldwide were limited to
non-pharmaceutical interventions such as isolation, quarantine, good personal hygiene, use of disinfectants, and limitations of public gatherings, which were applied unevenly.
By comparison to the wuhan coronavirus - the Spanish flu of 1918 is a different type of virus - and much more lethal.
The use of harvested antibodies from patients who have recoved from Wuhan coronavirus is a technique that has been previously used for other diseases - and is being researched now for use in severely affected patients.
It is likely the only truly specific treatment we may have to be developed in the near future.
It is done by taking blood from donors recovered from the infection - and harvesting the anti-coronavirus antibodies in the serum. Safe for the donors, reasonably safe for patients.
My info is that the technique post-dates the 1918 Spanish flu.
I am open to see your reference - DF.
Glad u brought up the topic.